Ponce Inlet is a town in Volusia County, Florida, United States. The population was 3,032 at the 2010 census. The town of Ponce Inlet is located on the southern tip of a barrier island, south of Daytona Beach and Daytona Beach Shores. Several marinas are located in Ponce Inlet.

Completed in 1887, replacing the former lighthouse (built-in 1835, it had collapsed into the inlet the following year), the Ponce de Leon Inlet Light Station was built when the area was known as Mosquito Inlet. After decades of restoration by the Ponce de Leon Inlet Lighthouse Preservation Association, it stands today as one of the best-preserved light stations in the nation.